GW-1516, also known as Cardarine, is a PPAR agonist that has been shown to positively affect muscle building, endurance, increased HDL (good) and decreased LDL (bad) cholesterol, and body recomposition. Cardarine currently has no human studies, but rodent studies have been very encouraging.
When combined with exercise in rodents, GW-501516 combined with four weeks of running increased running time by 68%; running distance by 70%; and doubled overall muscular endurance. Along with exercise, GW-1516 increased mitochondrial growth by 50%. Additionally, GW-1516 has been found to activate many of the genes that activate when an organism goes for a run or exercises.
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